Michael Eddleston Selected Research

Antidotes

1/2018	Anti-colchicine Fab fragments prevent lethal colchicine toxicity in a porcine model: a pharmacokinetic and clinical study.
6/2016	Plasma paracetamol concentration at hospital presentation has a dose-dependent relationship with liver injury despite prompt treatment with intravenous acetylcysteine.
1/2015	Fomepizole versus ethanol in the treatment of acute methanol poisoning: Comparison of clinical effectiveness in a mass poisoning outbreak.
3/2012	Quantification of pralidoxime (2-PAM) in urine by ion pair chromatography-diode array detection: application to in vivo samples from minipig.

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Michael Eddleston Research Topics

Disease

148	Poisoning 02/2024 - 01/2002
7	Vomiting 01/2023 - 09/2003
6	Respiratory Insufficiency (Respiratory Failure) 12/2022 - 01/2004
6	Organophosphate Poisoning 01/2021 - 10/2005
4	Bites and Stings (Sting) 01/2023 - 11/2004
4	Anaphylaxis (Anaphylactic Shock) 01/2022 - 11/2004
4	Hypotension (Low Blood Pressure) 01/2022 - 11/2008
4	Plant Poisoning 01/2021 - 01/2003
3	Snake Bites (Snake Bite) 01/2023 - 11/2004
3	Tachycardia (Tachyarrhythmias) 12/2021 - 12/2010
3	Confusion (Bewilderment) 12/2021 - 01/2017
3	Conjunctivitis 03/2017 - 02/2014
3	Shock 04/2012 - 10/2005
3	Seizures (Absence Seizure) 10/2010 - 01/2004
3	Status Epilepticus (Complex Partial Status Epilepticus) 09/2004 - 01/2003
2	Hallucinations (Hallucination) 12/2021 - 01/2019
2	Paralysis (Palsy) 12/2021 - 12/2021
2	Drug-Related Side Effects and Adverse Reactions 05/2019 - 10/2018
1	Alcoholism (Alcohol Abuse) 01/2023
1	Mental Disorders (Mental Disorder) 01/2023
1	Alzheimer Disease (Alzheimer's Disease) 12/2022
1	Lactic Acidosis 02/2022
1	Hirschsprung Disease (Hirschsprung's Disease) 01/2022
1	Contracture 01/2022

Drug/Important Bio-Agent (IBA)

78	PesticidesIBA 02/2024 - 01/2002
37	InsecticidesIBA 11/2023 - 01/2004
13	Acetaminophen (Paracetamol)FDA LinkGeneric 05/2019 - 06/2002
12	ParaquatIBA 01/2023 - 11/2005
11	PoisonsIBA 01/2022 - 01/2006
10	OximesIBA 12/2022 - 10/2005
10	Dimethoate (Rogor)IBA 01/2020 - 10/2005
9	pralidoxime (Protopam Chloride)FDA Link 02/2022 - 05/2008
8	AcetylcholinesteraseIBA 12/2022 - 06/2009
6	SolventsIBA 12/2022 - 04/2012
6	HerbicidesIBA 10/2022 - 09/2005
6	Methanol (Carbinol)IBA 01/2021 - 01/2015
6	Charcoal (Charbon)IBA 05/2013 - 09/2003
5	Chlorpyrifos (Lorsban)IBA 06/2023 - 10/2005
5	Acetylcysteine (Siran)FDA LinkGeneric 01/2020 - 02/2012
5	CarbamatesIBA 01/2019 - 12/2004
4	TabletsIBA 11/2023 - 11/2016
4	profenofosIBA 02/2022 - 09/2010
4	EnzymesIBA 01/2020 - 09/2010
4	AntidotesIBA 01/2018 - 03/2012
4	Nerve AgentsIBA 12/2014 - 09/2010
4	Digoxin (Digitek)FDA LinkGeneric 05/2013 - 01/2003
3	AluminumIBA 11/2023 - 11/2005
3	OrganophosphatesIBA 11/2023 - 07/2010
3	Antivenins (Antivenoms)IBA 01/2023 - 01/2003
3	dimethoxon (omethoate)IBA 01/2022 - 05/2010
3	Creatine Kinase (Creatine Phosphokinase)IBA 12/2021 - 09/2005
3	Methyl Parathion (Dalf)IBA 01/2021 - 12/2007
3	Ethanol (Ethyl Alcohol)IBA 01/2021 - 01/2015
3	Biomarkers (Surrogate Marker)IBA 12/2020 - 09/2014
3	Atropine FDA LinkGeneric 01/2020 - 11/2008
3	AntiemeticsIBA 05/2019 - 04/2013
3	Colchicine FDA LinkGeneric 01/2018 - 01/2003
3	Cholinergic Agents (Cholinergics)IBA 01/2018 - 05/2010
3	CardenolidesIBA 01/2018 - 12/2006
3	Glyphosate (Roundup)IBA 12/2012 - 09/2009
3	AntitoxinsIBA 09/2008 - 01/2003
3	EndosulfanIBA 04/2008 - 01/2003
2	Agrochemicals (Agricultural Chemicals)IBA 01/2023 - 12/2017
2	EmeticsIBA 01/2023 - 10/2022
2	Neuromuscular Blocking AgentsIBA 12/2022 - 01/2020
2	Lactic Acid (Lactate)FDA LinkGeneric 02/2022 - 04/2012
2	ElectrolytesIBA 01/2022 - 09/2005
2	Phosphates (Orthophosphate)IBA 01/2022 - 09/2010
2	SaltsIBA 01/2022 - 01/2020
2	CalciumIBA 01/2022 - 01/2022
2	CyclohexanolsIBA 12/2021 - 12/2021
2	Cyanides (Isocyanides)IBA 01/2020 - 10/2012
2	Aryldialkylphosphatase (Paraoxonase)IBA 01/2020 - 05/2008
2	2-(2'-pyridyldithio)benzyldiazoacetateIBA 01/2020 - 05/2008
2	Cholinesterase Inhibitors (Anticholinesterases)IBA 01/2018 - 12/2014
2	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 01/2018 - 01/2011
2	Immunoglobulin Fab FragmentsIBA 08/2017 - 01/2003
2	Detergents (Detergent)IBA 03/2017 - 02/2014
2	Ondansetron (Zofran)FDA LinkGeneric 02/2014 - 04/2013
2	Cardiac GlycosidesIBA 05/2013 - 01/2003
2	FenthionIBA 03/2012 - 10/2005
2	Chloride Channels (Chloride Channel)IBA 10/2010 - 01/2004
2	BenzodiazepinesIBA 10/2010 - 10/2002
2	BarbituratesIBA 10/2010 - 10/2002
2	Parathion (Ethyl Parathion)IBA 09/2010 - 05/2008
2	Organophosphorus CompoundsIBA 09/2010 - 01/2009
2	PropanilIBA 02/2009 - 01/2002
1	Donepezil (Aricept)FDA LinkGeneric 12/2022
1	piperidineIBA 12/2022
1	Neuromuscular Agents (Skeletal Muscle Relaxants)IBA 12/2022
1	AlginatesIBA 10/2022
1	phenthoate (Elsan)IBA 02/2022
1	Diazinon (Dimpylate)IBA 02/2022
1	Cholinesterases (Cholinesterase)IBA 02/2022
1	VenomsIBA 01/2022

Therapy/Procedure

8	Therapeutics 01/2023 - 01/2003
3	Artificial Respiration (Mechanical Ventilation) 01/2022 - 01/2009
3	Transcutaneous Electric Nerve Stimulation (TENS) 01/2020 - 02/2011
2	Resuscitation 01/2018 - 09/2003
2	Critical Care (Surgical Intensive Care) 01/2016 - 01/2009